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Publications

Scientific Literature

Articles on Biothera compounds that were published in peer-reviewed science and medical journals or presented in scientific forums:

September 2010

Enzymatic Method To Measure β-1,3-β-1,6-Glucan Content in Extracts and Formulated Products (GEM Assay).
Journal of Agricultural and Food Chemistry.
DOI:10.1021/jf102003m

May 2010

Influence of Continuous Intake of Glucopolysaccharide (GPS) Derived from Baker's Yeast on Mood and Emotional States.

Biotherapy (2010) 24 (3):255-259.


April 2010

Beta-glucan Supplement Reduces Upper Respiratory Tract
Infections and Improves Mood State in Healthy Stressed Subjects

Presented at Experimental Biology 2010 in Anaheim, Calif.

February 2010
Beta 1,3/1,6 Glucan Decreases Upper Respiratory Tract Infection Symptoms and Improves Psychological Well-being in Moderate to Highly-Stressed Subjects.
Agro Food Industry Hi-Tech (2010) 21:21-24.

December 2009
Effect of Beta 1, 3/1, 6 Glucan on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes.
Journal of Sports Science and Medicine (2009). 8:509-515.

July 2009
Randomized Phase II Clinical Trials of Wellmune WGP® for Immune Support During Cold and Flu Season.
The Journal of Applied Research (2009) 9:20-42.

February 2009

Therapeutic Potential of Various β-glucan Sources in Conjunction with Anti-tumor Monoclonal Antibody in Cancer Therapy.

Cancer Biology & Therapy. 8:3, 216-223; 1 February 2009.

September 2008
Effects of an Immunomodulating Supplement on Upper Respiratory Tract Infection Symptoms in Wildland Firefighters.
Medicine & Science in Sports & Exercise. 40(5):S353.


August 2008
Analysis of Side Chain Lengths of Branched β-1,3-Glucans by Alkaline Degradation.
A poster presentation at the International Carbohydrate Symposium in Oslo, Norway.

October 2007
WGP® 3-6 Supplement Reduces Immune Suppression and Improves Mood State in Stressed Subjects.
Journal of the American College of Nutrition. 26(5):484.

September 2007
Toxicological Assessment of a Particulate Yeast (1,3)-ß-D-Glucan in Rats.
Food and Chemical Toxicology (2007) 45:1719-1730.

August 2006
Yeast β-Glucan Amplifies Phagocyte Killing of iC3b-opsonized Tumor Cells via CR3-Syk-PI3-kinase Pathway.
The Journal of Immunology. 2006 Aug 1;177(3):1661-9

January 2006
Beta-Glucan Enhances Complemented-Mediated Hematopoietic Recovery after Bone Marrow Injury.
Blood. 15 January 2006. Volume 107, Number 2.

June 2005
C5a-Mediated Leukotriene B4-Amplified Neutrophil Chemotaxis is Essential in Tumor Immunotherapy Facilitated by Anti-Tumor Monoclonal Antibody and ß-Glucan.
The Journal of Immunology. 2005 174:7050-7056.

May 2005
Yeast Whole Glucan Particle ß-Glucan in Conjunction with Anti-tumour Monoclonal Antibodies to Treat Cancer.
Expert Opinion on Biological Therapy. May 2005, Vol. 5, No. 5, Pages 691-702.

July 2004
Mechanism by Which Orally Administered ß-1,3-Glucans Enhance the Tumoricidal Activity of AntiTumor Monoclonal Antibodies in Murine Tumor Models.
The Journal of Immunology. 2004: 173: 797-806.

March 2003
Anthrax-Protective Effects of Yeast Beta 1,3 Glucans.
Medscape General Medicine.

May 2002
Pilot Study: Orally-Administered Yeast ß1,3-glucan Prophylactically Protects Against Anthrax Infection and Cancer in Mice.
The Journal of the American Nutraceutical Association.
Vol. 5, No. 2, Spring 2002.