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EAGAN, MN – March 3, 2014 – Wellmune WGP®, the natural immune booster from Biothera, is a key ingredient in a reinvented immune health supplement from Twinlab, a leading North American supplement manufacturer and marketer. Twinlab Immunity Booster™ is launching during Natural Products Expo West March 7-9 in Anaheim and will be available nationally through health and natural foods stores and online through the Twinlab website.

Twinlab Immunity Booster Box

Wellmune is a beta 1,3/1,6 glucan derived from a proprietary strain of baker’s yeast. Nine human clinical studies consistently demonstrate the ability of Wellmune to safely boost key immune cells that help keep the body healthy. Research shows that high intensity exercise may temporarily weaken the immune system and over time may derail training programs and performance gains.

Wellmune is clinically tested to boost the immune system to help keep the body healthy. Published, peer-reviewed studies demonstrate that Wellmune mobilizes billions of innate immune cells that are part of the body’s natural defenses.

“We set out to develop a more robust, clinically relevant immune health supplement to meet growing consumer demand for immune support,” said Gene Bruno, MS, MHS, Director of Category Management, Twinlab Corp. “Wellmune is the ‘hero ingredient,’ given its deep portfolio of peer-reviewed, published human clinical research demonstrating efficacy for everyday immune support and upper respiratory health.”

“Twinlab Immunity Booster containing Wellmune is an exciting new option for consumers seeking an effective way to help stay well,” said Richard G. Mueller, CEO, Biothera. “Launch during the Spring season is timely. It’s a good reminder that immune support is an everyday need year round, and not just seasonal.”

Twinlab Immunity Booster is available in a 90-capsule bottle. Three capsules daily will deliver the clinically tested serving of 250 mg of Wellmune. The suggested retail price is $29.99.

Wellmune is currently in food, beverages and supplements in more than 60 countries around the world.

About Twinlab®
Twinlab Corporation is a leading manufacturer and marketer of high quality, science-based, nutritional supplements and sports nutrition products. Since 1968, the Twinlab brand has manufactured and marketed nutritional supplements in both the vitamin and sports nutrition categories. In addition to its namesake brand, Twinlab Corporation also manufactures and sells other well-known category leaders including the Metabolife® line of diet and energy products; Fuel® line of sports supplement products; Alvita® teas, established in 1922 as a single-herb tea line; Trigosamine® joint support products as well other health and wellness brands. Twinlab’s manufacturing facility in American Fork, Utah is an NSF GMP registered facility. Twinlab also runs a scientific and regulatory facility in Grand Rapids, Michigan; and has its corporate headquarters in New York, NY. Visit www.twinlab.com for more information.

About Wellmune WGP®
Wellmune WGP is a proprietary baker’s yeast beta 1,3/1,6 glucan that is clinically shown to prime key immune cells that keep the body healthy. This natural food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China. It is also patented, Kosher, Halal, non-allergenic and GMO-free. Wellmune is the 2013 recipient of the NBT Award for Outstanding Application in Health Management. It has also received an IFT Innovation Award, a SupplySide West Scientific Excellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

Biothera Media Contact:
David Walsh
VP Communications
Biothera, the Immune Health Company
dwalsh@biothera.com
651-256-4606

Twinlab Media Contact:
Susan Fecko
Percepture
sfecko@percepture.com
303-449-8381

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SunRype FruitActiv™ Immuniboost™ bars with Wellmune.

SunRype FruitActiv™ Immuniboost™ bars with Wellmune WGP®.



EAGAN, MN – February 26, 2014 – Wellmune WGP®, the natural immune booster from Biothera, is now in a line of fruit and whole grain bars from a leading fruit snack manufacturer. The FruitActiv™ Immuniboost™ bars from British Columbia-based Sun-Rype Products Ltd., are available at grocery stores, supermarkets, mass merchandisers and club channel stores throughout Canada.

Wellmune is a natural beta 1,3/1,6 glucan derived from a proprietary strain of baker’s yeast. Wellmune is clinically proven to safely boost the immune system to keep the body healthy. Eight published, peer-reviewed studies demonstrate that Wellmune mobilizes billions of innate immune cells that are part of the body’s natural defenses, without over stimulating the immune system.

“Sun-Rype’s R&D department is highly skilled at developing formulations that maximize taste while incorporating functional ingredients with meaningful benefits, such as clinically proven Wellmune WGP for immune support,” said Barb Broder, Group Marketing Manager-Food, Sun-Rype. “With the addition of our FruitActiv Immuniboost line containing Wellmune, boomers and other health-conscious consumers now have an easy way to give their immune system a boost with the goodness of a fruit and whole grain snack.”

“Bars are an ideal delivery vehicle for Wellmune’s everyday, year-round immune support,” said Richard G. Mueller, Biothera Chief Executive Officer. “The FruitActiv Immuniboost bars align with key consumer trends – on the go convenience, wholesome ingredients and functional benefits.”

The bars are available in a choice of Mango Twist or Orange Squeeze flavors. Each bar contains 100 mg of Wellmune. The suggested retail price per bar is $1.49-$1.99.

Currently, there are more than 100 products with Wellmune in more than 60 countries around the world.

About SunRype
Sun-Rype Products Ltd., based in Kelowna, BC, is a manufacturer and marketer of fruit-based juices and snacks. For more information visit www.sunrype.com.

About Wellmune WGP®
Wellmune WGP is a proprietary baker’s yeast beta 1,3/1,6 glucan that is clinically proven to prime key immune cells that keep the body healthy. This natural food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China. Wellmune is available in products in more than 60 countries around the world. It is also patented, Kosher, Halal, non-allergenic and GMO-free. Wellmune is the 2013 recipient of the NBT Award for Outstanding Application in Health Management. It has also received an IFT Innovation Award, a SupplySide West Scientific Excellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

Contact:
David Walsh
VP Communications
Biothera, the Immune Health Company
651-256-4606
dwalsh@biothera.com

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Glycobiology[1]Research Published in Glycobiology

EAGAN, MN – February 13, 2014 – Wellmune WPG®, the immune health ingredient for foods, beverages and supplements from Biothera, utilizes distinct receptors and signaling pathways in certain white blood cells to induce cytotoxic function.The research was published in the latest issue of the peer-reviewed journal Glycobiology.

This new research describes how structurally different forms of yeast beta glucans utilize different receptors and associated signaling pathways to activate innate immune functions.Wellmune WGP is yeast-derived beta glucan that boosts innate immune cells that help keep the body healthy.

“This research further elucidates the mechanisms through which Wellmune WGP primes immune responses in key immune cells to enhances the body’s defenses,” said Don Cox, Ph.D., senior vice president of Biothera’s Healthcare Group’s R&D. “It also demonstrates that beta-glucan structure is a critical attribute in eliciting biological effects.”

In the study, different forms of Biothera beta glucan were used to activate human peripheral blood mononuclear cells and oxidative burst, one of the cytotoxic mechanisms used by innate immune cells. Both particulate and soluble forms of Biothera beta glucans bound to either complement receptor 3 (CR-3) or receptor Dectin-1 to initiate an immune response. These physically different forms of beta glucan induced this functional response through both overlapping and distinct signaling pathways.

The paper is entitled, “Differential regulation of oxidative burst by distinct β-glucan-binding receptors and signaling pathways in human peripheral blood mononuclear cells.”

The authors include Nandita Bose1, Lindsay R. Wurst1, Anissa SH. Chan1, Christine M. Dudney1, Megan L. LeRoux1, Michael E. Danielson1, Paul M. Will1, Sonja E. Nodland1, Myra L. Patchen1, Jurandir J. Dalle Lucca2, Frank J. Lebeda3, and John P. Vasilakos1.

1 Biothera, Eagan, MN 55121 USA
2 US Army Institute of Surgical Research, Ft. Sam Houston, 78234 USA TX
3 US Army Medical Research and Materiel Command, Ft. Detrick, MD 21701 USA

About Wellmune WGP®
Wellmune WGP is a proprietary baker’s yeast beta 1,3/1,6 glucan that is clinically proven to prime key immune cells that keep the body healthy. This natural food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China. Wellmune is available in more than 100 products in more than 50 countries around the world. It is also patented, Kosher, Halal, non-allergenic and GMO-free. Wellmune is the 2013 recipient of the NBT Award for Outstanding Application in Health Management. It has also received an IFT Innovation Award, a SupplySide West Scientific Excellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

Contact:
David Walsh
VP, Communications
Biothera, the Immune Health Company
651-256-4606
dwalsh@biothera.com

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Come along on a behind-the-scenes look at how Cleveland, Ohio-based Fun Treats makes its freezer pops that contain immune booster Wellmune and a prebiotic. John Allman from Fun Treats explains how these freezer pops make it easy for kids to have a refreshing treat that also helps keep them well.

In the coming months, Fun Treats will be coming to a store near you!

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UntitledEAGAN, MN –Jan. 13, 2014 – U!be Group Inc., a leading product innovator in the health and wellness category in Taiwan, has selected Wellmune WGP®, the natural immune health ingredient from Biothera, for a new children’s lozenge, U!be Strong®. This is the second U!be Super Kids series product focused on immune and oral health for children and the first lozenge with Wellmune.

Wellmune is clinically proven to safely boost the immune system to keep the body healthy. Eight published, peer-reviewed studies demonstrate that Wellmune mobilizes billions of innate immune cells that are part of the body’s natural defenses, without over stimulating the immune system.

“U!be Strong® children’s lozenge was created to help parents maintain their children’s immune health in today’s harsh environment and hectic lifestyle,” said John Perng, Ph.D., U!be Group Inc.’s vice president of R&D and Business Development. “Upper respiratory tract infection (URTI) and allergy symptoms due to weakened immunity are all too common in modern-day, school-age children. We know from years of experience that Wellmune, with its U.S. FDA-notified GRAS status and solid body of clinical research, is the top immune-enhancing ingredient available. What we are doing now is to expand its benefit into the children’s nutritional products arena.”

“We are excited that U!be Group Inc. has chosen to incorporate Wellmune into its children nutritional product for Chinese markets throughout the world,” said Richard G. Mueller, Biothera chief executive officer.

Mueller added, “As consumers look for more ways to support their health and vitality, the broader availability of clinically proven Wellmune in brands they trust, offers peace of mind and worry-free convenience that contributes to healthy habits for a lifetime.”

About U!be Group Inc.
U!be Group Inc. is a pioneer in creating innovative nutraceutical products featuring clinically proven nutraceutical ingredients and novel delivery systems. The company’s goal is to provide natural solutions to health problems with its U!be brand of products that is efficacious yet affordable to the general public.

About Wellmune WGP®
Wellmune WGP is a proprietary baker’s yeast beta 1,3/1,6 glucan that is clinically proven to prime key immune cells that keep the body healthy. This natural food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China. Wellmune is available in more than 100 products in more than 60 countries around the world. It is also patented, Kosher, Halal, non-allergenic and GMO-free. Wellmune is the 2013 recipient of the NBT Award for Outstanding Application in Health Management. It has also received an IFT Innovation Award, a SupplySide West Scientific Excellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

Contact:
David Walsh
VP Communications
Biothera, the Immune Health Company
651-256-4606 (direct)
dwalsh@biothera.com

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Dietitians and others interested in novel dietary immune boosting interventions to help protect against the effects of stress (like immune booster Wellmune) can now access our newest webinar, Nutrition for a Stressed-Out World.The complimentary webinar is Stressed womanpresented by John Blocher, Ph.D., of the Biothera team. We are pleased to make the webinar available through February 6, 2014, via the Sports, Cardiovascular and Wellness Nutrition (SCAN) dietary practice group of the Academy of Nutrition and Dietetics (see Viewing Instructions below).

The topic is timely given the pervasive stressors in our lives and the fact that stress is on the rise and is associated with numerous health issues. While acute or short-term stress can enhance immune response, chronic or long-term stress can suppress immunity. A growing body of evidence links nutrition to immune health. In this webinar, Dr. Blocher provides a refresher on how the immune system works and surveys common dietary interventions. He will also present findings from human clinical research examining the role of Wellmune in the diet for boosting immunity to protect against the negative effects of physical and psychological stress.

Viewing Instructions
While the webinar is free, to gain access create a guest account and obtain a log-in on the SCAN website. You’ll “order” the webinar via the following link: http://www.scandpg.org/store/products/10236/.

Once the webinar is “purchased” for free, go into “My Profile.” The media files along with pdf of the powerpoint and a quiz to obtain continuing education credit for dietitians (if desired) are accessible in “My Media.”

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Ortho Molecular Products is now offering products to the healthcare professional market containing natural immune health ingredient Wellmune WGP®. The company recently introduced WholeMune capsules with Wellmune and has other WholeMune with Natural Immune Booster Wellmuneproducts in the pipeline, including a convenient 10-count WholeMune blister pack, to meet a wide range of patient needs.

Each WholeMune capsule contains the recommended daily serving of 250mgs of Wellmune.

“Biothera is a respected leader in immune research and we are excited to partner with them. Wellmune’s extensive clinical research underscores its effectiveness and meets our demand for ingredients that have proven results,” said Aaron Bartz, president of Ortho Molecular Products.

“Managing immune challenges is a well-recognized need to support overall health and wellness,” said Richard G. Mueller, chief executive officer, Biothera. “Designed for everyday use year-round, Wellmune is the ideal ingredient for WholeMune to deliver clinically proven immune health benefits including helping to manage the harmful effects of physical and psychological stress. Backed by extensive science, Wellmune is the immune booster that healthcare professionals can recommend with confidence.”

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In this short video, Roger Clemens, DrPH, and Scientific Advisor to the Wellmune brand discusses why it’s important to boost the immune system daily to help keep the body healthy. This is the latest video in a series from members of our board of scientific advisors.

For more short educational videos from our advisors and other experts, visit the Wellmune channel on YouTube.

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 EAGAN, MN – Nov. 13, 2013 – Wellmune WGP®, the natural immune booster from Biothera, is the active ingredient in the new Immune Fit™ bulk powder from MRI, a leading manufacturer of nutraceuticals to support sports performance.

Wellmune is a beta 1,3/1,6 glucan derived from a proprietary strain of baker’s yeast. Nine human clinical studies consistently demonstrate the ability of 6780 IMMUNE FIT #3F401Wellmune to safely boost key immune cells that keep the body healthy. Research shows that high intensity exercise may temporarily weaken the immune system and over time may derail training programs and performance gains.

Clinical research with marathoners, cyclists and others enduring high physical stress demonstrate how Wellmune can support immune defenses before, during and after exercise. Additionally, in multiple clinical studies Wellmune reduced the incidence of upper respiratory tract infection symptoms that commonly afflict distance runners and other athletes.

“Most athletes plan their training in order to reach milestones by a specific period,” said Grace Manzano, director of marketing, Sports Nutrition, for MRI/PROLAB. “If they get sick, that down time sets them back a few training days, forcing them to deviate from their plan. Wellmune’s clinically proven ability to help athletes stay in the ‘Healthy Zone’ longer is compelling. It is an ideal asset to the MRI Performance line for people with active lifestyles.”

“Both competitive and recreational athletes can benefit from the everyday immune health benefits of Wellmune to sustain energy, sharpen mental clarity and support their overall health,” said Richard G. Mueller, CEO, Biothera. “MRI’s development of Immune Fit is testament to the market need for an immune booster to keep athletes well and the clinical evidence supporting Wellmune’s benefit to athletes.”

Immune Fit will be available in specialty stores, online and through other MRI distribution channels reaching people with active lifestyles. Each serving of Immune Fit includes the recommend 250 mg of Wellmune, the clinically proven effective serving. For more information about Immune Fit visit www.mri-performance.com.

Currently, there are more than 100 products with Wellmune in more than 60 countries around the world.

About Wellmune WGP®
Wellmune WGP is a proprietary baker’s yeast beta 1,3/1,6 glucan that is clinically proven to prime key immune cells that keep the body healthy. This natural food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China. Wellmune is available in more than 100 products in more than 50 countries around the world. It is also patented, Kosher, Halal, non-allergenic and GMO-free. Wellmune is the 2013 recipient of the NBT Award for Outstanding Application in Health Management. It has also received an IFT Innovation Award, a SupplySide West Scientific Excellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

Contact:
David Walsh
VP Communications
Biothera, the Immune Health Company
651-256-4606 (direct)
dwalsh@biothera.com

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 In this brief video, scientific advisor to the Wellmune brand Roger Clemens, DrPH, and past president of the Institute of Food Technologists, underscores the importance examining the quality, quantity and consistency of research conducted on a functional ingredient.

Dr. Clemens notes that in the arena of immune health ingredients, Wellmune is a standout. He explains what to look for on an ingredient label to assure the ingredient panel contains clinically proven immune booster Wellmune. Wellmune clinical research

Consumers are interested in the health benefits of boosting immunity. Consider that in a 2012 study published in the Journal of the American Medical Association, immune health was one of the top three reasons consumers took supplements in the past two years. “Immune health” was cited more often than “pain relief,” “weight control” or “reducing heart attacks.” The compelling safety and efficacy research supporting Wellmune make it an ideal ingredient for delivering the real health benefits that consumers want.